Multidrug-resistant Acinetobacter lwoffii infection in a diabetic patient

Abstract

Introduction: Diabetic foot ulcer is one of the main complications of patients with diabetes and has become a major cause of non-traumatic amputation. 60 % of diabetic foot ulcers can become infected with microorganisms, increasing the risk of amputation by 50 % compared to patients with non-infected foot ulcers. Antimicrobial resistance is a global phenomenon that has reached alarming levels.

Objective: To report a case of amputation of a patient with diabetic foot ulcer and Acinetobacter lwoffi infection.

Case presentation: It is presented a case of a patient diagnosed with a deep abscess-type neuroinfectious diabetic foot. Bacteriological examination revealed the presence of Acinetobacter lwoffii resistant to almost all antibiotics, except doxycycline. The patient required amputation of the limb as definitive therapy to control sepsis.

Conclusions: The evolution of this germ began very sensitive to common antimicrobials, but after a rapid adaptation, it became first resistant, then multidrug-resistant and then pandrug resistant, a term coined exclusively for this type of germ.