Periodontitis and its Association with Peripheral Arterial Disease
Keywords:
periodontitis; peripheral arterial disease; oral health; atherosclerosisAbstract
Introduction: Periodontitis and peripheral arterial disease are prevalent chronic disorders that share common risk factors and inflammatory mechanisms.
Objective: To critically analyze the scientific evidence on the association between periodontitis and peripheral arterial disease.
Methods: A literature review was conducted in PubMed, Scopus, Redalyc, and VHL, following PRISMA criteria, including original studies and reviews from 2000-2025.
Results: The analysis was organized into five thematic axes: common risk factors, pathophysiological mechanisms, epidemiological and clinical evidence, clinical implications, and future perspectives.
Conclusions: Periodontitis may contribute to the onset and progression of peripheral arterial disease through systemic inflammation, endotelial dysfunction, and oxidative stress; in turn, peripheral arterial disease may worsen periodontal health. A multidisciplinary clinical approach and further longitudinal research are recommended.
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Copyright (c) 2025 Brenda Noland Ferrer, Alberto Adrián Mártir González, Daniel Reynaldo Concepción, Elizabeth Portal Fernández
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
ESTA REVISTA PUBLICA EN ACCESO ABIERTO, por lo que los autores ni los lectores deberán pagar para realizar sus envíos ni leer los artículos publicados.
Esta obra está bajo una Licencia de Creative Commons Reconocimiento-NoComercial 4.0 Internacional.
